Therapeutical Product Index
Our continually growing product portfolio includes more than 70 products in different indication groups. Learn more about our products.
Diclo-Denk 100 Rectal I 10 Retard I Diclo-Denk 50

Benefits
- Individualized treatment with different formulation dosages.
- Strong anti-inflammatory drug with an excellent anti-inflammatory and anti-rheumatic action.
- Fast acting – effective after only 30 min.
Documented bioequivalence
Diclo-Denk 100 Rectal in comparison with the original product:

Doloforte Denk

Benefits
- Doloforte Denk: 325 mg paracetamol, 37.5 mg tramadolhydro-chloride
- Useful treatment for moderate to severe pain and fever
- Rapidly-acting, longer-duration, multimodal analgesic
- Wide indication range - due to high analgesic efficiency and synergistic effects
- Easy administration with fixed-dose combination
Proven bioequivalence

Dologan Denk

Benefits
- 250 mg paracetamol, 250 mg ibuprofen, 50 mg caffeine
- Indicated for mild to moderate pain, migraines, arthritis, fever and colds
- Broad spectrum of activity – combination of different synergistic effects
- More rapid onset of action and stronger effects - via caffeine adjunct
- Lower dosage = Reduction of adverse effects: Caffeine reduces the relative analgesic portions
ParaCo-Denk 500/30 I ParaCo-Denk 1000/60 Suppos

Benefits
- 500 mg / 1000 mg paracetamol + 30 mg / 60 mg codeine
- Effective combination of paracetamol and codeine
- Recommended for effective relief from moderate to severe pain (WHO pain ladder Step 2)
- Reduces daily dose of NSAIDs and codeine
- Less side effects than monotherapies
- For patients with high cardiovascular or gastrointestinal risk
- No hemodilution
- Long lasting effect
- Gluten- and lactose-free
Tramadol Denk 50mg

Benefits
- 50 mg tramadol
- Centrally acting analgesic, used for the treatment of moderately severe to severe pain - fast acting pain relief
- Multimodal mechanism of action - acute and chronic pain
- Very fast effect
- No bleeding
- No gastric or cardiovascular side effects
- Proven tramadol-safety profile over decades
- Recommended by WHO Guidelines
- Gluten- and lactose-free
Denk-Air 10 mg I Denk-Air Junior 4 mg I Denk-Air Junior 5 mg

Benefits
- 4 mg / 5 mg / 10 mg montelukast (as montelukast sodium)
- Very good compliance – orally, once daily
- Generally well tolerated without clinically important adverse effects
- Most potent inhibitor of Leukotriene-induced bronchoconstriction
- Safe for children from 2 years and older (Denk-Air Junior 4 mg)
- Available as chewable tablets - convenient dosage form for children
Documented bioequivalence
Denk Air 5 mg and 10 mg in comparasion with the original product.

Amoxi-Denk 500 I Amoxi-Denk 1000

Benefits
- 500 mg / 1000 mg amoxicillin
- Superior safety profile amongst amino-penicillins
- One of the best absorption rates of all antibiotics: 80%
- Resulting in less impairment of gastric flora
- Extremely rare gastrointestinal side-effects
Documented bioequivalence
Amoxi-Denk 500 in comparison with the original product:

AmoxiClav-Denk 500/62.5 I AmoxiClav-Denk 1000/125

Benefits
- 500 mg / 1000 mg amoxicillin + 62.5 mg / 125 mg clavulanic acid
- Fast, broad-spectrum antibiotic for otitis media, respiratory, kidney, gastric and uro-genital infections
- Effective potency through the addition of synergistic clavulanic acid
- Reliable compliance with tablets or with powder for oral suspension and balanced formulation of amoxicillin and clavulanic acid
Documented bioequivalence
AmoxiClav-Denk im comparision with the original product:

Cipro-Denk 500 I Cipro-Denk 750

Benefits
- 500 mg / 750 mg ciprofloxacin
- High level of activity against Escherichia coli
- Most effective against Pseudomonas aeruginosa
- Well-established in infections of bones and joints, and the respiratory tract
Documented bioequivalence
Bioequivalence Cipro-Denk 750 in comparison with the original product:

Doxy-Denk 100 I Doxy-Denk 200

Benefits
- 100 mg / 200 mg doxycyclin
- Standard therapy of respiratory infections and several other intracellular infections such as Chlamydia/Rickettsiosis/Migrans/Lyme disease
- Long term treatment possible
- Once daily
Documented Bioequivalence
Doxy-Denk 200 in comparison with the original product:

Levo-Denk 250 I Levo-Denk 500

Benefits
- 250 mg / 500 mg levofloxacin
- Broad microbiological spectrum antibiotic - Treatment of serious bacterial infections
- Wide variety of indications - potent "respiratory fluoroquinolone"
- Once daily - good compliance
- Generally well tolerated
Documented Bioequivalence
Levo-Denk 500 in comparison with the original product:

Levoflox-Denk 5mg/ml

Benefits:
- 5 mg/ml levofloxacin: Solution for infusion, intravenous use – for hospital use
- Treatment of serious bacterial infections, especially hospital-acquired infections
- Broad microbiological spectrum antibiotic - wide variety of indications
- Effective and generally safe (few side effects)
- Many clinical practice guidelines recommend this product
Grani-Denk 1 mg / ml

Benefits
- 1 mg granisetron / 1 ml resp. 3 mg granisetron/ 3 ml concentrate for solutions for injection or infusion
- Selective serotonin 5-HT3 receptor blocker
- Indicated in chemotherapy-, radiotherapy and post-operative induced nausea & vomiting
- Benzyl alcohol free solution
- Safe and effective in elderly and children
On.setron-Denk 4 I On.setron-Denk 8

Benefits
- 4 mg / 8 mg ondansetron
- Indicated in chemotherapy, radiotherapy and post-operative induced nausea & vomiting
- Rapidly disintegrating oral tablets, free from lactose and gluten
- Low incidence of drug interactions
- Safe and effective in elderly and children
- Guideline listed 5-HT3 receptor antagonists
Documented bioequivalence
On.setron Denk 8 mg in comparasion with the original product.

Asu-Denk fixed dose

Benefits
- 500 mg sulfamethoxypyrazine + 200 mg artesunate + 25 mg pyrimethamine
- Safe, simple and stable
- 3 tablets 3 days
- Better compliance
- Less risk drug resistance
- Fast onset
- Low recurrence
- Take the full course of treatment
- Unique bi-layer tablet for better stability
- Aluminium /Aluminium blister foil protects against humidity
Acyclovir Denk 200 I Acyclovir Denk 5% Cream

Benefits
- Minimal risk of interactions with other medicinal drugs or food.
- Low toxicity – Acyclovir attacks only herpes infected cells, not healthy cells of the body.
- Well-tolerated with mild side effects.
Documented bioequivalence
Acyclovir Denk in comparison with the original product:

Flucona-Denk 100 I Flucona-Denk 150

Benefits
- 100 mg / 150 mg fluconazole
- Very effective to treat different kinds of yeast infections
- Flucona-Denk 100 is used for fungal infections caused by yeasts
- Flucona-Denk 150 is used for vaginal fungal infections caused by yeasts that do not respond to a local therapy
Documented Bioequivalence
Flucona-Denk 150 in comparison with the original product:

Voriconazol Denk 200mg

Voriconazol Denk 200mg
- Safe and effective in elderly and children (>12 years).
- High oral bioavailability (96%) switching between intravenous and oral administration is possible.
- Guideline recommended for the treatment of invasive aspergillosis (first-line) and non-neutropenic candidemia (alternative regimen) by the IDSA (Infectious Diseases Society of America).
Carvedi-Denk 6.25 I Carvedi-Denk 25

Benefits
- 6.25 mg / 25 mg carvedilol
- Used for heart / circulatory diseases
- Two in one β / α - double action - Carvedilol is both a beta blocker (β1, β2) and alpha blocker (α1)
- Lowers blood pressure by reducing the workload of the heart, which is particularly beneficial in heart failure patients
Documented Bioequivalence
Carvedi-Denk 25 in comparison with the original product:

Clopi-Denk 75

Benefits
- 75 mg clopidogrel
- Prevention and treatment of atherothrombotic events including acute coronary syndrome and thromboembolic events in atrial fibrillation
- Proven in mono, dual and triple therapy
- Antiplatelet inhibitor of choice in patients who do not undergo invasive strategies, but alternative medical treatment in ACS
- Once daily - good compliance
Documented bioequivalence
Clopi-Denk 75 in comparison with the original product:

Ena-Denk 10 I Ena-Denk 20 I Ena + HCT-Denk 20/12.5

Benefits
- Ena-Denk: 10 mg / 20 mg enalapril
Ena + HCT-Denk: 20 mg enalapril + 12.5 mg hydrochlorothiazide - Reduces mortality by 50%
- Retards the progression of the disease
- Improves the pathology
Documented bioequivalence
Ena-Denk 10 in comparison with the original product:

Losar-Denk 25 / 50 / 100 I CoLosar-Denk 50/12.5 I CoLosar-Denk 100/12.5

Benefits
- Losar-Denk: 25 mg / 50 mg / 100 mg losartan
CoLosar-Denk: 50 mg / 100 mg losartan + 12.5 mg hydrochlorothiazide - Effectively reduces the blood pressure with no effect on the heart rate
- Reduces the risk of stroke with no more dry cough
- Excellent once-daily compliance
- Safe in patients with renal disease and diabetic nephropathy
- Proven indication in hypertensive children above age of 6 years
- Fixed dose hydrochlorothiazide for additional adequate control of blood pressure
Documented bioequivalence
Losar-Denk 100 mg in comparison with the original product:

Nifedi-Denk 10 Retard I Nifedi-Denk 20 Retard

Benefits
- 10 mg / 20 mg nifedipine
- Slow release calcium channel blocker
- Consistent blood pressure control
- Effective over 12 hours
- Recommended for long-term control of hypertension
- Minimizes side effects
Documented bioequivalence
Nifedi-Denk 20 Retard in comparison with the original product:

arthro active Denk

Benefits
- Unique combination of rosehip extract, collagen hydrolysate, hyaluronic acid, vitamin C and vitamin K supports the strength of joints, cartilage and bones.
- Strong bones are important for maintaining the mobility and resilience of joints and cartilage.
- With anti-inflammatory ingredients.
D3 Junior Denk

Benefits
- Vitamin D plays an important role in the development and maintenance of healthy bones, teeth and a normal muscle function
- Contributes to a healthy immune system
- With 500 IU (International Units) = 12.5 µg Vitamin D3
- Adjusted dosage for infants’ individual needs
- Easy administration for infants - dissolvable in a spoonful of water
Digest Active Denk

Benefits
- A high-quality nutrient combination of artichoke, milk thistle, zinc and calcium that supports the function of the digestive system
- With its antioxidant properties, milk thistle supports healthy liver function
- Artichoke, zinc and calcium support bile production, fatty acid metabolism and the function of digestive enzymes
Electrolyte Denk

Benefits
- Hypotonic electrolyte-glucose mixture for fast replenishment of electrolytes and water after fluid loss
- Composition derived from the latest WHO recommendations. - The right amount of electrolytes is able to support the regeneration of the body after fluid loss
- Oral solution with fruity lemon grapefruit taste
ferro vital+ Denk

Benefits
- Iron, vitamin C and folic acid contribute to the reduction of tiredness and fatigue
- Contains microencapsulated iron for extremely high bioavailability and enhanced iron absorption
- High tolerance due to sustained release of active ingredients
- Chewable tablets with fruity berry taste
immun active Denk

Benefits
- Effective combination of vitamin C, zinc, L-histidine and selenium that supports the body’s immune defences
- Supports both the innate and adaptive immune system
- Vitamin C, zinc and selenium contribute to the protection of cells from oxidative stress
- L-histidine supports zinc absorption
- Direct sticks with fruity raspberry taste perfect for on the go
Prenatal +DHA Denk

Benefits
- Ideal supply of folic acid, vitamins, micronutrients and docosahexaenoic acid (DHA)
- Omega-3 fatty acid docosahexaenoic acid (DHA) for healthy foetal and infantile development of the brain and retina
- Recommended from the 13th week of pregnancy and can be used until the end of breastfeeding
prenatal Denk

Benefits
- Ideal supply of folic acid, vitamins and micronutrients from planning a family and for the first 12 weeks of pregnancy
- Folic acid for a healthy neural tube development and for supporting the process of cell division
- With 800 µg folic acid for an increased need before and during pregnancy
vitactive B12 Denk

Benefits
- Contains vitamin B12 and the amino acids L-glutamine and L-serine to support performance of both body and mind
- Vitamin B12 contributes to energy-yielding metabolism, functioning of the nervous system and the reduction of tiredness and fatigue
- L-glutamine and L-serine play important roles in brain function and functioning of the central nervous system
Tadala Denk 20mg

Tadala Denk
- Recommended first-line therapy for erectile dysfunction.
- Fast effect (within 30 minutes) and long duration up to 36 hours.
- Not affected by food or moderate alcohol consumption.
For more information please visit our patient website www.tadala-denk.com
Panto-Denk 20 I Panto-Denk 40

Benefits
- 20 mg / 40 mg pantoprazole
- Treatment of mild, moderate and severe reflux diseases
- Very effective and safe
- Lactose and gluten free tablets
- Good compliance - once daily
- High healing rates and successful relief of symptoms
Documented bioequivalence
Panto-Denk 40 in comparison with the original product:

Glimepiride 2 I Glimepiride 3

Benefits
- 2 mg / 3 mg glimepiride
- Once daily - convenient and safe
- Low rate of side effects - improved patient compliance
- Well-tried add-on-combinations
- Most efficient - effective glycaemic control (HbA1c - 2%)
- Cardio protective - preserves ischemic preconditioning
- Improves lipoprotein metabolism - statistical significance
- Safe and effective for long term - less risk of mortality
Documented bioequivalence
Glimepiride Denk in comparision with the original product:

Metformin Denk 500 I Metformin Denk 850 I Metformin Denk 1000

Benefits
- 500 mg / 850 mg / 1000 mg metformin
- No risk of hypoglycaemia
- Promote weight reduction
- Patient-friendly film-coated tablet:
- neutral in taste
- easier to swallow
- better stability
- can be easily divided
Documented bioequivalence
Metformin Denk in comparison with the original product:

Rosuvastatin Denk 5mg / 10mg / 20mg

Rosuvastatin Denk 5mg / 10mg / 20mg
- Most effective statin in lowering LDL-Cholesterol and triglycerides.
- Highest HDL-C increasing effect and consistent across all dose ranges.
- ESC (European Society of Cardiology) recommends statins for the primary prevention of cardiovascular events.
Simva-Denk 20 I Simva-Denk 40

Benefits
- 20 mg / 40 mg simvastatin
- Excellent, proven cholesterol synthesis inhibitor
- Prevents plaque, protects the vessels
- First-line adjunct therapy for diabetics
- Patient-friendly: breakable tablet
Documented bioequivalence
Simva-Denk 40 in comparison with the original product:

Imatinib Denk 100 mg I Imatinib Denk 400 mg

Benefits
- Guideline-recommended for the treatment of chronic myeloid leukemia (CML).
- Easy to take (orally, once daily with a meal and a large glass of water).
- May be dispersed in fluid if patient has swallowing problems.
Proven bioequivalence
Imatinib Denk 100 mg in comparison with the original product:

Zoledro-Denk 4 mg / 5 ml

Benefits
- One vial with 5 ml concentrate contains 4 mg zoledronic acid (as monohydrate)
- Zoledro-Denk prevents skeletal related events in patients with advanced malignancies involving bone fractures in patients with cancers, and treats tumor-induced hypercalcemia, osteoporosis (post-menopausal women and in men; even with a recent low-trauma hip fracture; also associated with long-term systemic glucocorticoid therapy) and Paget’s disease of the bone
- Strong inhibition of osteoclastic bone resorption
- Showed significant benefit in osteoporosis as well as reduction in mortality after hip fraction